Paying cash for medication is increasingly a great option for people with high co-pays with health insurance or people without insurance. But knowing where and how to get the best price is often difficult. Two systems are for cash paying are compared: GoodRx which is a tech company that acts as a middleman at chain pharmacies. Direct Primary Care are where medications are dispensed directly to their patients.

Pharmacy benefit managers (PBMs) are essentially middlemen who negotiate with drug manufacturers on behalf of health insurers, large employers and others that contract them. The nature of how PBMs operate has changed radically over the years.